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    "headline": "A Liver Treatment Starts With the Gut Barrier",
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    "dek": "Michigan Medicine says DT-109 reversed severe fatty-liver disease in animal models by repairing intestinal defenses and limiting toxin exposure.",
    "summary": "Michigan Medicine says DT-109 reversed severe fatty-liver disease in animal models by repairing intestinal defenses and limiting toxin exposure.",
    "body_text": "Michigan Medicine researchers tested the experimental compound DT-109 in animal models of metabolic dysfunction-associated steatohepatitis. The treatment restored gut-barrier function and reduced the passage of damaging microbial products into circulation, while the animals showed reversal of severe disease markers. The work remains preclinical, but it supports treating MASH as a connected gut-liver system instead of a single-organ problem.",
    "why_it_matters": "Michigan Medicine says DT-109 reversed severe fatty-liver disease in animal models by repairing intestinal defenses and limiting toxin exposure.",
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      "The work remains preclinical, but it supports treating MASH as a connected gut-liver system instead of a single-organ problem."
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        "qualification": "The work remains preclinical, but it supports treating MASH as a connected gut-liver system instead of a single-organ problem."
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      "published_at": "2026-07-10T20:00:00.000-04:00",
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    "title": "A Liver Treatment Starts With the Gut Barrier",
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