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    "headline": "The Cell's Ribosome Factory Has Rooms Within Rooms",
    "slug": "the-cell-s-ribosome-factory-has-rooms-within-rooms",
    "dek": "St. Jude researchers found spontaneous sub-compartments that hold late-stage building blocks together inside the nucleolus.",
    "summary": "St. Jude researchers found spontaneous sub-compartments that hold late-stage building blocks together inside the nucleolus.",
    "body_text": "The nucleolus is a liquid-like organelle where cells assemble ribosomes, but its internal organization is more layered than the familiar three-compartment model. St. Jude researchers found smaller sub-compartments inside the granular component, where RNA and assembly proteins concentrate with SURF6 and NPM1 to keep late-stage ribosome parts in place. The structures form spontaneously through molecular interactions rather than membranes. Mapping that organization may help explain diseases marked by excessive ribosome production, including some cancers, though the study itself identifies cell biology rather than a therapeutic target ready for use.",
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    "first_published_at": "2026-07-16T09:00:00.000-04:00",
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    "tags": [
      "nucleolus",
      "ribosomes",
      "cell biology",
      "condensates"
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      "title": "St. Jude via Newswise: Nucleolus sub-compartments drive ribosome assembly",
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      "published_at": "2026-07-15T18:40:00.000-04:00",
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    "title": "The Cell's Ribosome Factory Has Rooms Within Rooms",
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