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    "headline": "Oral Precancer Builds an Immune Blind Spot Early",
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    "dek": "SOX2-amplified cells recruit suppressive myeloid cells before invasive cancer is established.",
    "summary": "SOX2-amplified cells recruit suppressive myeloid cells before invasive cancer is established.",
    "body_text": "MD Anderson models showed SOX2-amplified cells releasing CCL2 and inflammatory signals that recruit suppressive myeloid cells. Blocking the IL-1 receptor reduced those cells, delayed tumors, and improved survival. This identifies a possible immunoprevention route, not a patient-ready treatment.",
    "why_it_matters": "SOX2-amplified cells recruit suppressive myeloid cells before invasive cancer is established.",
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      "This identifies a possible immunoprevention route, not a patient-ready treatment."
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    "modified_at": "2026-07-17T14:34:04.943-04:00",
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        "qualification": "This identifies a possible immunoprevention route, not a patient-ready treatment."
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    "tags": [
      "oral cancer",
      "immunoprevention",
      "inflammation"
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    {
      "source_id": "source-2026-07-17-005",
      "title": "MD Anderson via Newswise: Early inflammation drives oral cancer",
      "publisher": "MD Anderson via Newswise",
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      "published_at": "2026-07-16T19:25:00.000-04:00",
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    "title": "Oral Precancer Builds an Immune Blind Spot Early",
    "publisher": "The Machine Press",
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