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    "headline": "Two Tumor Targets Fit Into One DNA-Delivered Dose",
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    "dek": "Wistar's preclinical platform makes bispecific T-cell engagers in the body and combines two ovarian-cancer targets.",
    "summary": "Wistar's preclinical platform makes bispecific T-cell engagers in the body and combines two ovarian-cancer targets.",
    "body_text": "Wistar researchers reported a knob-into-hole antibody design delivered as DNA, allowing cells to produce bispecific T-cell engagers after dosing. A two-target version is intended to reduce escape when a tumor loses one antigen. The work improved ovarian-cancer control in preclinical models; it is not evidence of safety or benefit in patients.",
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    "tags": [
      "ovarian cancer",
      "immunotherapy",
      "bispecific antibodies"
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      "title": "Wistar via Newswise: DNA-delivered ovarian cancer immunotherapy",
      "publisher": "The Wistar Institute via Newswise",
      "url": "https://www.newswise.com/articles/wistar-scientists-develop-dna-delivered-immunotherapy-that-targets-ovarian-cancer-more-effectively",
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      "published_at": "2026-07-17T18:30:00.000-04:00",
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    "title": "Two Tumor Targets Fit Into One DNA-Delivered Dose",
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