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    "headline": "Removing Brain Immune Cells Restored Sleep in Mice",
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    "dek": "A temporary microglia depletion reversed sleep loss in an Alzheimer's model without changing amyloid plaques.",
    "summary": "A temporary microglia depletion reversed sleep loss in an Alzheimer's model without changing amyloid plaques.",
    "body_text": "University of Kentucky researchers temporarily depleted about 87 percent of microglia for 14 days in a mouse model of Alzheimer's disease. The animals recovered more than two hours of sleep per day, chiefly non-REM sleep, even though amyloid plaque burden did not change. The result points toward immune signaling as a contributor to disrupted sleep in this model. It is a short preclinical experiment and does not establish a safe or effective treatment for people.",
    "why_it_matters": "A temporary microglia depletion reversed sleep loss in an Alzheimer's model without changing amyloid plaques.",
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      "The animals recovered more than two hours of sleep per day, chiefly non-REM sleep, even though amyloid plaque burden did not change.",
      "It is a short preclinical experiment and does not establish a safe or effective treatment for people."
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        "qualification": "The animals recovered more than two hours of sleep per day, chiefly non-REM sleep, even though amyloid plaque burden did not change."
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    "tags": [
      "Alzheimer's disease",
      "microglia",
      "sleep"
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    {
      "source_id": "source-2026-07-20-004",
      "title": "University of Kentucky via ScienceDaily: Microglia and sleep",
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    "title": "Removing Brain Immune Cells Restored Sleep in Mice",
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