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    "headline": "One Blood-Vessel Cell Guides T Cells Into Metastases",
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    "dek": "LPL-producing endothelial cells act as entry guides for activated immune cells in liver metastases.",
    "summary": "LPL-producing endothelial cells act as entry guides for activated immune cells in liver metastases.",
    "body_text": "A DKFZ and Heidelberg University team identified a specialized endothelial-cell subgroup inside liver metastases that produces lipoprotein lipase. These cells help activated T cells cross tumor blood vessels and enter metastatic tissue, connecting vascular metabolism to immune access. The finding may help explain why some tumors respond poorly to immunotherapy and suggests a route for improving infiltration. It remains mechanistic research, not a validated therapy for patients with liver metastases.",
    "why_it_matters": "LPL-producing endothelial cells act as entry guides for activated immune cells in liver metastases.",
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      "It remains mechanistic research, not a validated therapy for patients with liver metastases."
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        "text": "LPL-producing endothelial cells act as entry guides for activated immune cells in liver metastases.",
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        "qualification": "It remains mechanistic research, not a validated therapy for patients with liver metastases."
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    "tags": [
      "metastases",
      "T cells",
      "endothelium"
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  "sources": [
    {
      "source_id": "source-2026-07-21-014",
      "title": "German Cancer Research Center via EurekAlert: Vessels guide immune cells",
      "publisher": "German Cancer Research Center via EurekAlert",
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    "title": "One Blood-Vessel Cell Guides T Cells Into Metastases",
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