{
  "$schema": "https://themachinepress.com/schemas/story-v1.schema.json",
  "schema_version": "1.0.0",
  "document_type": "machine_press_story",
  "story": {
    "story_id": "mp-2026-07-23-009",
    "source_story_id": "tmp-story-focused-ultrasound-pancreatic-trial",
    "edition_id": "mp-2026-07-23-morning-0014",
    "edition_url": "https://themachinepress.com/edition/2026-07-23",
    "position": 9,
    "story_type": "dispatch",
    "section": "research",
    "editorial_classification": "editorial",
    "headline": "Focused Ultrasound Moved More Patients Toward Surgery",
    "slug": "focused-ultrasound-moved-more-patients-toward-surgery",
    "dek": "A 60-person Phase II study paired ultrasound with FOLFIRINOX and compared outcomes with a matched historical cohort.",
    "summary": "A 60-person Phase II study paired ultrasound with FOLFIRINOX and compared outcomes with a matched historical cohort.",
    "body_text": "A Seoul National University Hospital Phase II trial enrolled 60 people with borderline-resectable or locally advanced pancreatic cancer; 56 completed focused ultrasound plus FOLFIRINOX. Compared with 56 propensity-matched historical controls, the combination group had higher tumor response, longer median survival, and more curative-intent surgeries. The nonrandomized comparison is encouraging but cannot establish the benefit as firmly as a randomized trial.",
    "why_it_matters": "A 60-person Phase II study paired ultrasound with FOLFIRINOX and compared outcomes with a matched historical cohort.",
    "limitations": [
      "The nonrandomized comparison is encouraging but cannot establish the benefit as firmly as a randomized trial."
    ],
    "importance": 9,
    "canonical_url": "https://themachinepress.com/story/mp-2026-07-23-009/focused-ultrasound-moved-more-patients-toward-surgery",
    "json_url": "https://themachinepress.com/story/mp-2026-07-23-009.json",
    "first_published_at": "2026-07-23T09:00:00.000-04:00",
    "modified_at": "2026-07-23T09:00:00.000-04:00",
    "content_status": "new",
    "is_carryover": false,
    "carryover_reason": null,
    "key_claims": [
      {
        "claim_id": "claim-mp-2026-07-23-009-001",
        "text": "A 60-person Phase II study paired ultrasound with FOLFIRINOX and compared outcomes with a matched historical cohort.",
        "source_ids": [
          "source-2026-07-23-009"
        ],
        "qualification": "The nonrandomized comparison is encouraging but cannot establish the benefit as firmly as a randomized trial."
      }
    ],
    "source_ids": [
      "source-2026-07-23-009"
    ],
    "tags": [
      "pancreatic cancer",
      "focused ultrasound",
      "clinical trial"
    ],
    "image_url": null,
    "corrections": []
  },
  "sources": [
    {
      "source_id": "source-2026-07-23-009",
      "title": "Focused Ultrasound Foundation via Newswise: Pancreatic cancer Phase II trial",
      "publisher": "Focused Ultrasound Foundation via Newswise",
      "url": "https://www.newswise.com/articles/focused-ultrasound-may-enhance-chemotherapy-survival-outcomes-for-pancreatic-cancer-study-finds",
      "canonical_url": "https://www.newswise.com/articles/focused-ultrasound-may-enhance-chemotherapy-survival-outcomes-for-pancreatic-cancer-study-finds",
      "source_type": "official_announcement",
      "is_primary_source": true,
      "published_at": null,
      "accessed_at": "2026-07-23T08:34:00.000-04:00",
      "supports_claim_ids": [
        "claim-mp-2026-07-23-009-001"
      ]
    }
  ],
  "corrections": [],
  "publisher": {
    "name": "The Machine Press",
    "url": "https://themachinepress.com",
    "description": "A daily newspaper for the age of artificial intelligence."
  },
  "cite_this_report": {
    "title": "Focused Ultrasound Moved More Patients Toward Surgery",
    "publisher": "The Machine Press",
    "published_at": "2026-07-23T09:00:00.000-04:00",
    "canonical_url": "https://themachinepress.com/story/mp-2026-07-23-009/focused-ultrasound-moved-more-patients-toward-surgery"
  }
}
