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    "story_id": "mp-2026-07-23-026",
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    "headline": "The Immune Signal Appeared a Decade Before the Diagnosis",
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    "dek": "Antibody profiles in nearly 2,000 stored blood samples distinguished people who later developed inflammatory bowel disease.",
    "summary": "Antibody profiles in nearly 2,000 stored blood samples distinguished people who later developed inflammatory bowel disease.",
    "body_text": "Mount Sinai researchers examined nearly 2,000 blood samples collected over about a decade from people who later developed Crohn's disease or ulcerative colitis. Antibody signatures appeared years before clinical diagnosis, offering a view of IBD's preclinical phase. The retrospective profiling does not create a screening test and cannot determine whether an individual with a marker will develop disease.",
    "why_it_matters": "Antibody profiles in nearly 2,000 stored blood samples distinguished people who later developed inflammatory bowel disease.",
    "limitations": [
      "Antibody signatures appeared years before clinical diagnosis, offering a view of IBD's preclinical phase.",
      "The retrospective profiling does not create a screening test and cannot determine whether an individual with a marker will develop disease."
    ],
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    "first_published_at": "2026-07-23T09:00:00.000-04:00",
    "modified_at": "2026-07-23T09:00:00.000-04:00",
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        "text": "Antibody profiles in nearly 2,000 stored blood samples distinguished people who later developed inflammatory bowel disease.",
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        "qualification": "Antibody signatures appeared years before clinical diagnosis, offering a view of IBD's preclinical phase."
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    "tags": [
      "inflammatory bowel disease",
      "antibodies",
      "early detection"
    ],
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  "sources": [
    {
      "source_id": "source-2026-07-23-015",
      "title": "Mount Sinai via Newswise: Preclinical IBD antibody signatures",
      "publisher": "Mount Sinai Health System via Newswise",
      "url": "https://www.newswise.com/articles/mount-sinai-study-detects-immune-changes-up-to-10-years-before-inflammatory-bowel-disease-is-diagnosed",
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      "accessed_at": "2026-07-23T08:34:00.000-04:00",
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    "title": "The Immune Signal Appeared a Decade Before the Diagnosis",
    "publisher": "The Machine Press",
    "published_at": "2026-07-23T09:00:00.000-04:00",
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