{
  "$schema": "https://themachinepress.com/schemas/story-v1.schema.json",
  "schema_version": "1.0.0",
  "document_type": "machine_press_story",
  "story": {
    "story_id": "mp-2026-07-24-010",
    "source_story_id": "tmp-story-recall-by-genotype",
    "edition_id": "mp-2026-07-24-morning-0015",
    "edition_url": "https://themachinepress.com/edition/2026-07-24",
    "position": 10,
    "story_type": "dispatch",
    "section": "research",
    "editorial_classification": "editorial",
    "headline": "The Biobank Called Back the Rare-Variant Carriers",
    "slug": "the-biobank-called-back-the-rare-variant-carriers",
    "dek": "A diverse health-system study measured what it takes to recruit people by genotype for deeper psychiatric assessment.",
    "summary": "A diverse health-system study measured what it takes to recruit people by genotype for deeper psychiatric assessment.",
    "body_text": "Mount Sinai researchers invited 892 BioMe participants to follow-up studies: 335 carried rare copy-number variants linked to neurodevelopmental risk, 217 had schizophrenia without those variants, and 340 were controls. Eighteen percent responded and 8% completed detailed assessments, which revealed traits missed in routine records. The result is an operational benchmark for recall-by-genotype research, not a diagnostic program or evidence that a variant determines an individual outcome.",
    "why_it_matters": "A diverse health-system study measured what it takes to recruit people by genotype for deeper psychiatric assessment.",
    "limitations": [
      "The result is an operational benchmark for recall-by-genotype research, not a diagnostic program or evidence that a variant determines an individual outcome."
    ],
    "importance": 8,
    "canonical_url": "https://themachinepress.com/story/mp-2026-07-24-010/the-biobank-called-back-the-rare-variant-carriers",
    "json_url": "https://themachinepress.com/story/mp-2026-07-24-010.json",
    "first_published_at": "2026-07-24T09:00:00.000-04:00",
    "modified_at": "2026-07-24T09:28:00.000-04:00",
    "content_status": "new",
    "is_carryover": false,
    "carryover_reason": null,
    "key_claims": [
      {
        "claim_id": "claim-mp-2026-07-24-010-001",
        "text": "A diverse health-system study measured what it takes to recruit people by genotype for deeper psychiatric assessment.",
        "source_ids": [
          "source-2026-07-24-010"
        ],
        "qualification": "The result is an operational benchmark for recall-by-genotype research, not a diagnostic program or evidence that a variant determines an individual outcome."
      }
    ],
    "source_ids": [
      "source-2026-07-24-010"
    ],
    "tags": [
      "biobanks",
      "genetics",
      "psychiatry"
    ],
    "image_url": null,
    "corrections": []
  },
  "sources": [
    {
      "source_id": "source-2026-07-24-010",
      "title": "Mount Sinai via Newswise: Recall-by-genotype biobank study",
      "publisher": "Mount Sinai via Newswise",
      "url": "https://www.newswise.com/articles/study-demonstrates-recall-by-genotype-in-a-healthcare-system-biobank-advancing-precision-psychiatry",
      "canonical_url": "https://www.newswise.com/articles/study-demonstrates-recall-by-genotype-in-a-healthcare-system-biobank-advancing-precision-psychiatry",
      "source_type": "secondary_reporting",
      "is_primary_source": false,
      "published_at": null,
      "accessed_at": "2026-07-24T09:24:00.000-04:00",
      "supports_claim_ids": [
        "claim-mp-2026-07-24-010-001"
      ]
    }
  ],
  "corrections": [],
  "publisher": {
    "name": "The Machine Press",
    "url": "https://themachinepress.com",
    "description": "A daily newspaper for the age of artificial intelligence."
  },
  "cite_this_report": {
    "title": "The Biobank Called Back the Rare-Variant Carriers",
    "publisher": "The Machine Press",
    "published_at": "2026-07-24T09:00:00.000-04:00",
    "canonical_url": "https://themachinepress.com/story/mp-2026-07-24-010/the-biobank-called-back-the-rare-variant-carriers"
  }
}
