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    "story_id": "mp-2026-07-31-013",
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    "headline": "A Negative BRCA Test Did Not Erase Family Risk",
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    "dek": "Ontario records placed lifetime breast-cancer risk near 25% for referred women without a pathogenic BRCA result.",
    "summary": "Ontario records placed lifetime breast-cancer risk near 25% for referred women without a pathogenic BRCA result.",
    "body_text": "Cedars-Sinai researchers analyzed records for nearly 16,000 Ontario women tested between 2007 and 2016. In this referred, family-history-enriched group, those without a pathogenic BRCA1 or BRCA2 result still had an estimated 25% lifetime breast-cancer risk, while women with variants of uncertain significance were near 30%. The observational study supports risk assessment beyond a binary genetic result; it does not apply the same estimate to every person with a negative test.",
    "why_it_matters": "Ontario records placed lifetime breast-cancer risk near 25% for referred women without a pathogenic BRCA result.",
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      "The observational study supports risk assessment beyond a binary genetic result; it does not apply the same estimate to every person with a negative test."
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    "first_published_at": "2026-07-31T09:00:00.000-04:00",
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        "text": "Ontario records placed lifetime breast-cancer risk near 25% for referred women without a pathogenic BRCA result.",
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        "qualification": "The observational study supports risk assessment beyond a binary genetic result; it does not apply the same estimate to every person with a negative test."
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    "tags": [
      "BRCA",
      "family history",
      "breast cancer",
      "risk assessment"
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      "source_id": "source-2026-07-31-013",
      "title": "Cedars-Sinai via Newswise: Family history after BRCA testing",
      "publisher": "Cedars-Sinai",
      "url": "https://www.newswise.com/articles/study-family-history-increases-cancer-risk-in-brca-tested-patients",
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      "accessed_at": "2026-07-31T08:31:33.328-04:00",
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  "cite_this_report": {
    "title": "A Negative BRCA Test Did Not Erase Family Risk",
    "publisher": "The Machine Press",
    "published_at": "2026-07-31T09:00:00.000-04:00",
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