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A Gut Metabolite Tracks With an Irregular Rhythm
Higher TMAO levels were associated with atrial fibrillation and electrical changes in a large clinical cohort and cell studies.
Summary
Higher TMAO levels were associated with atrial fibrillation and electrical changes in a large clinical cohort and cell studies.
Cleveland Clinic researchers studied more than 5,000 people undergoing heart procedures and found that higher trimethylamine N-oxide levels were associated with atrial fibrillation. Laboratory experiments also linked TMAO exposure to changes in the electrical environment of heart cells. The clinical finding is observational and does not show that changing diet or TMAO alone will prevent the rhythm disorder.
Why it matters
Higher TMAO levels were associated with atrial fibrillation and electrical changes in a large clinical cohort and cell studies.
Limits and context
- Laboratory experiments also linked TMAO exposure to changes in the electrical environment of heart cells.
- The clinical finding is observational and does not show that changing diet or TMAO alone will prevent the rhythm disorder.
Key claims
Higher TMAO levels were associated with atrial fibrillation and electrical changes in a large clinical cohort and cell studies.
Qualification: Laboratory experiments also linked TMAO exposure to changes in the electrical environment of heart cells.
Evidence: source-2026-07-25-009
Sources
- Cleveland Clinic via Newswise: TMAO and atrial fibrillationCleveland Clinic via Newswise · secondary reporting
Corrections
No corrections have been recorded for this story.