research
One Conjugate Blocked Two Metastasis-Linked Proteases
A protein-small-molecule prototype inhibited MMP-9 and KLK6 and reduced cell migration and invasion.
Summary
A protein-small-molecule prototype inhibited MMP-9 and KLK6 and reduced cell migration and invasion.
The conjugate outperformed the separate inhibitors, alone or mixed, in colorectal and pancreatic cancer cell lines without reducing viability. This is an in-vitro therapeutic prototype, not evidence of safety or benefit in animals or people.
Why it matters
A protein-small-molecule prototype inhibited MMP-9 and KLK6 and reduced cell migration and invasion.
Limits and context
- This is an in-vitro therapeutic prototype, not evidence of safety or benefit in animals or people.
Key claims
A protein-small-molecule prototype inhibited MMP-9 and KLK6 and reduced cell migration and invasion.
Qualification: This is an in-vitro therapeutic prototype, not evidence of safety or benefit in animals or people.
Evidence: source-2026-08-03-019
Sources
- Scientific Reports: bispecific MMP-9 and KLK6 inhibitorSpringer Nature · secondary reporting
Corrections
No corrections have been recorded for this story.