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The Citation Exists. It Still Supports the Wrong Claim.

Biomedical agents almost always produced real PubMed identifiers in closed-book mode, but almost none were relevant to the claim.

Published Updated Story ID: mp-2026-10-22-026
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Summary

Biomedical agents almost always produced real PubMed identifiers in closed-book mode, but almost none were relevant to the claim.

A controlled SciFact study compared closed-book answers, single-shot PubMed retrieval, a query-writing agent and access to gold abstracts. Of 335 closed-book citations, 327 PubMed identifiers existed, yet an independent judge found only three relevant to the claim. Letting the agent write queries tripled gold-paper recall and reached 62 percent verdict accuracy; gold abstracts lifted the same models to 79 to 86 percent, pointing to retrieval as the main bottleneck. The realistic-harness accuracy differences were not statistically significant at the sample size.

Why it matters

Biomedical agents almost always produced real PubMed identifiers in closed-book mode, but almost none were relevant to the claim.

Limits and context

  • Of 335 closed-book citations, 327 PubMed identifiers existed, yet an independent judge found only three relevant to the claim.
  • The realistic-harness accuracy differences were not statistically significant at the sample size.

Key claims

  1. Biomedical agents almost always produced real PubMed identifiers in closed-book mode, but almost none were relevant to the claim.

    Qualification: Of 335 closed-book citations, 327 PubMed identifiers existed, yet an independent judge found only three relevant to the claim.

    Evidence: source-2026-10-22-015

Sources

  1. arXiv preprint 2610.29812, original v1arXiv · primary research

Corrections

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